Edit: managed to boot by reinstalling grub, reinstalling the kernel (latest) with Artix’ own basestrap script and then updating grub from a live USB. System saved. Now it won’t accept a new IP from my dhcp server but that’s tomorrow’s problem. Thank you all for your quick respones! 🥰
Artix Linux
Thinkpad T480
Symptoms appeared after a system upgrade

Error log:
[ 0.801115] VFS: Cannot open root device "UUID=ed827e9a-47e4-490c-8a9a-0f0145925e0b" or unknown-block(0,0): error -6
[ 0.801117] Please append a correct "root=" boot option; here are the available partitions:
[ 0.801119] List of all bdev filesystems:
[ 0.801119] ext3
[ 0.801120] ext2
[ 0.801121] ext4
[ 0.801122] fuseblk
[ 0.801122] btrfs
[ 0.801123]
[ 0.801124] Kernel panic - not syncing: VFS: Unable to mount root fs on unknown-block(0,0)
Should I adjust something in fstab from a live USB or can I point to the root partition from GRUB’s CLI?


And you can mount the partition in your live USB boot?
It sounds like your bootloader doesn’t recognize the file system at that device path.
Mounted no problem. Deleted everything under /boot when chrooted and reinstalled grub. Now, grub doesn’t even load at boot, it just takes me to the UEFI. There, I see the “grub” entry, but it’s inaccessible.
At least on Ubuntu, /boot also has the initrd and kernel (vmlinuz). Maybe your distribution has them in /, but if not, you probably need to reinstall the kernel package in the chroot.